She should be fine except it may cause GI (stomach) upset because it’s something different. My biggest concern is that yorkies tend to be small and an upset stomach could lead to dehydration etc. So, if she does have an upset stomach (vomiting and diarrhea) more than 1 or 2 episodes I would take her to the vet for treatment.
Good Luck
Dr Dawn
It does sound like a reaction to his vaccinations. If he is not feeling better by tomorrow I recommend taking him back to the vet.
Good Luck
Dr Dawn