Our female German Shepherd dog is 5 years old and has had chronic liquid diarrhea for 5 months. Other symptoms are weight loss, sporadic inappetence and vomiting. Her energy is normal and bright. History of Pika, but no obvious ingestion of foreign objects during this interval. Three fecal studies mostly negative, two blood panels not conclusive (some levels low-normal). Two courses of Metronidazole (no effect), Three courses Amoxi/Clav (effective until finished), Panacur, probiotics, Cobalequin, special diets. Now on Hills GI Biome diet. Negative for EPI. Low B12. Vet has advised that this is antibiotic responsive diarrhea.

Went to an internal medicine specialist today upon referral. Ultrasound shows a tumour and intestinal thickening, lymph node activity. We are being steered toward open surgery to resect the intestine for possible, but unknown, malignancy and removal. Vet cannot explain why the diarrhea is antibiotic responsive, if malignant tumour. We are doing yet another expanded fecal study and Pancreatitis test to determine if coincident. We are already $3,800 into diagnostics with no real answers or help as to the root cause. Dog improves significantly with normal stools while on the Amoxi/Clav, but regresses immediately to liquid diarrhea when treatment stops.

Surgery recommended that may or may not be curative ($6,500). Of course, we hate to put our dog through this if futile, but understand that cancer cannot be diagnosed through imaging. Can anyone offer insights to either affirm our path or offer alternative ideas? Why the improved response to the antibiotics if a tumour is the cause? Thank you kindly.