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Stacy Brown | 3 years ago
My Polish Lowland Sheep Dog Has Had Cushings Disease For Past 2 Years. He Is…

My polish lowland sheep dog has had Cushings disease for past 2 years. He is on trilostane .25ml once per day. About 3 weeks ago he was diagnosed with diabetes. He is on 6 units of insulin
2x per day. The problem is he must eat in order to take the insulin and he is not hungry. We have tried everything. I didn’t give him the trilostane this morning and was able to get him to eat some chicken. Then I gave him the insulin. Suggestions?
Also, what about a pet cpd oil?

1 Response

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  1. Krista Magnifico

    Hello,
    I have many patients who have this dilemma. It is frustrating I know. I cant answer this specifically for your pet because a whole slew of variables influence the disease and therefore the patient. I would say to first start with a really thorough exam with a vet who is very versed in managing these diseases. I would also discuss repeating a full blood work to include a urinalysis. I look for problems expecting that this is what is affecting my patient. I know it is not what anyone wants to hear, but ignoring but not looking isn’t going to help anyone in the long run.. Lots of diabetics have infection hiding somewhere. Most often the urine.. I also always worry about hypothyroidism.. which makes pets lethargic. If everything is clear we start talking about diet, snacks, activity level, etc.
    A good diet for DM is imperative. If they are reluctant to eat it we do a very very gradual transition.
    It sounds like your pet might be having a problem right now, speciifcally, not in the eating in the past? correct? if so it is time to see the vet to see if the diabetes is the problem, or the cushings, or something new. No one, probably ot even your vet is going to be able to tell you what is influencing the not wanting to eat without an exam and blood work. I would check the blood sugar first, and talk about the last time the Cushings was looked at. It sounds like you need to call your vet now,, don’t do anything without talking to them. I tell my clients to not give insulin if their pet isnt eating, The worst thing they can do is give insulin without food,,, jic the blood sugar is already low.
    I have lately been putting Freestyle Libres on my new diabetic patients, or, those having problems, so the owners can scan and check at home easily. I have youtube videos on them.

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Martha Arias | 4 years ago
My Mini Poodle Had His 10 Year Old Bday. In March He Was Diagnosed With…

My Mini poodle had his 10 year old bday. In March he was diagnosed with cushings disease and diabetes. His health went downhill and we were both beyond shocked of the sudden impact these conditions took over his health. He’s on insulin twice a day, medication for the Cushings and his dietary meals has changed. After 3 intense, petrifying, and overwhelming months, I am thrilled to say pet’s blood sugar and endocrine levels are stable. I wanted to tell people who are dealing with these two horrible diseases – NOT to give up on your pet. My dog is blind because he developed cataracts from the diabetes and he’s acclimated extremely well. Be patient !!!!! As Dr. Kristin said in one of her blogs – it’s a manageable disease – be patient with our pet, and learn as much as we can about each disease. I wanted to thank you Dr. Kristin because for a brief moment – I almost gave up on him -?- ( I was petrified and so was he after sudden onset of blindness) but reading your blog gave me hope ! ? “Sam” and I are doing really well – blind and all he manages to greet me at the door when I come home ! Thank you ? Dr Kristin !

1 Response

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  1. Krista Magnifico

    Hello Martha and Sam!
    I am so glad to hear about Sams recovery and your courage in getting through two tough diseases. I know how scary and overwhelming it can feel as you ask yourself the myriad of questions that caring and treating a pet requires. It is a process. Sometimes painful and often expensive but it reminds us who we are and why fighting and protecting the lives of those we care about is so vital to being a compassionate and dedicated pet parent. I wish you and Sam many more happy days ahead. Be well and we will be here to support and stand beside you both if you need us. Xoxo! Krista.

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Martha Arias | 4 years ago
My 10 Y.o. Mini Poodle Was Diagnosed With Diabetes And Cushings Disease, Simultaneously. He’s…

My 10 y.o. Mini poodle was diagnosed with diabetes and Cushings disease, simultaneously. He’s on daily insulin injections and vetoryl for two months now but now his eyes are full of cataracts and is blind. I’m devastated and overwhelmed. He’s depressed and it breaks my heart. He’s a great dog – and I can’t afdord surgery – ! Does anyone know if dogs stay depressed or can they overcome their blindness. Desperately looking for real answers.

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  1. abby webster

    Maybe try a Vet that has knowledge in complementary medicine/supplements/acupuncture/etc. Sometimes these methods are less expensive than surgery and can help alleviate side effects of diseases and medications. I’m so sorry about your dog. I know how helpless you can feel, since they can’t tell us how they’re feeling!

  2. Krista Magnifico

    Hello,
    The blindness is typically due to the diabetes. I would say that overwhelmingly almost all of my diabetics go blind due to cataracts. It is very common. BUT all of them acclimate well and do live long (years) happy lives. I do urge you to learn as much as you can about both diseases and ask your vet and staff for help in understanding how you can help manage them at home to Bette regulate him and save you money. For instance many of my clients buy the vet recommended glucometer and do the curves and checks at home. Also you can ask for OTC insulin (often much cheaper!) and otc diets that might be better (pls understand the prescription options are often better but much more $$) to help control his blood sugar. In general we do everything we can to help clients manage their pets affordably so people aren’t feeling forced to give up or overwhelmed. Find a vet you trust and can depend on helping you.

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Natalie Dukes | 6 years ago
Wondering If My Dog Has Cushings… My 7 Year Australian Terrier Was Diagnosed With Pancreatitiis…

Wondering if my dog has cushings… My 7 year Australian terrier was diagnosed with pancreatitiis 2 years ago. She had IV and PO Antibiotics and her condition greatly improved. My 10 year old terrier just died from acute cushings disease and diabetes and kidney infection. I was worried about my Australian terrier so I had her blood tested on Oct 4. Most of her bloodwork came back normal. Her Magnesium was 2.7 (high) cholesterol was 401 (high)triglycerides were 872 high),alp was 742 (high). She had 20-30 WBC in her urine. Everything else was normal. She’s had a problem with skin allergies and infection from biting the skin. She was given a kenalog shot mid August.

1. Does it sound like she has Cushings to you?
2. Do you think the kenalog was responsible for these abnormal labs. She’s drinking and wetting normal amounts. No increased appetite. She’s asymptomatic. She needs to lose some weight d/t lack of excercise which I am starting to change. When I first got her, I had a good paying job and I could afford my 2 dogs. Now I’ve had to retire and money is very tight. I don’t know what to do. I know I don’t want to lose another dog. I really love her. What do you suggest?

1 Response

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  1. Krista Magnifico

    Hello,
    My deepest sympathies on the loss of your pup. I know how devastating it can be to loose a beloved pet. I am sorry but I cannot offer an opinion on this as I don’t know your dog and cushings requires an exam, correlation of clinical signs and additional testing. I do however feel that you paid for bloodwork and you deserve a thorough explanation and interpretation of this from your vet. I also think that explaining your fears and concerns and even budget is important. We are all vets to help our clients and patients and we are understanding when finances are a concern too.
    And as a side note I can say definitively that I would never treat or even encourage a client to do the workup ans spend money (especially if funds are tight) on an asymptomatic dog.
    I hope this helps.
    Krista

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Dan McGrady | 6 years ago
My Vet Wants To Prescribe Vetoryl For My Dog With Atypical Cushing’s Disease. Since She…

My Vet wants to prescribe Vetoryl for my dog with Atypical Cushing’s Disease. Since she already has below normal levels of cortisol, won’t this make her health worse? How could Vetoryl help in this instance?

1 Response

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  1. Krista Magnifico

    Hello,
    I am always leery about jumping into a case I know nothing about. Atypical Cushings is an especially tough one. My best advice is to seek a second opinion from an internal medicine specialist. I have to admit I hear this diagnosis thrown around much more than I actually believe it exists and I always confirm it before jumping into an expensive and potentially dangerous treatment and disease monitoring protocol. I feel that my clients need to be very well informed of price, prognosis, and expected course of the disease with both treating AND not treating.
    Very best of luck

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Lindsay Ayers | 6 years ago
So My Cat Franky Used To Sleep In My Bed Every Single Night He Was…

So my cat Franky used to sleep in my bed every single night he was the type of cat who loved to cuddle with you he did this since he was a kitten. The way he became my cat was that I found him when he was a kitten on a farm and he was infested with fleas and malnourished and I took him in and took care of him got him neutered etc. he was an indoor / outdoor cat but he preferred to be indoors. he was always pretty healthy except for when he was about 7 or 8 years old he was having trouble urinating he would Squat in the box and nothing would come out or if so only a little bit. so when I took him to the vet they saw that he was blocked but during his stay at the vet he was able to urinate on his own. probably a month or so later this occurred again and the same thing happened he ended up urinating on his own. he got blocked a third time and the doctor put him under anesthesia and had to unblock him the doctor said he found a lot of crystals in his urethra. this experience caused Franky a lot of stress and he kept to himself more at home. Franky, like I said used to sleep with me every single night no matter what he still slept with me after this experience. About a year or year and a half after that he just randomly stopped sleeping in my bed. I would try to bring him down to my bed but he would always seem very uncomfortable and restless and he would get up and scratch at the door wanting to get out. I kept trying to have him sleep with me but I eventually just accepted that he didn’t want to sleep in my bed anymore. he had a look of distress in his eyes often at this time as well.. I assumed that this may be caused by his traumatic experience at the vet when he was unblocked. this went on for quite a while where Franky did not seem himself but I always thought it was just related to trauma from the vet experience. maybe about a year after he was unblocked I noticed he started to look thinner but he had a very hearty appetite. so I decided to bring him to the vet regarding his weight loss I didn’t think it was anything serious. the vet who looked at him took blood work and she said she doesn’t know what is wrong with him but whatever it is it is not good at all. I took him to another vet and they did more blood tests all the blood tests were coming back normal the only test that wasnt normal was the urine protein creatinine level it was slightly elevated so the doctor started putting him on urinary diet and assuming this was kidney related. but he said that he really wasn’t sure because all the other levels of his blood work were normal his thyroid was checked and it was normal they did stool sample test they checked his glucose level. the vets did everything they could think of. I took Franky to another vet and we decided to do an ultrasound of his abdomen nothing was found. they said it looked normal but yet franky kept losing weight the doctor gave me antibiotics to try and a few other medications but these only seem to make it worse Frankie started having horrible explosive diarrhea he was not having the diarrhea before he went on the medication. I stopped the medication completely but the diarrhea continued it did not stop ever Franky’s appetite increased a lot he was always hungry but so skinny at this point. Franky went from A nine and a half pound cat to a four and a half pound cat by the time he passed away. I took him another vet and they had a feeling he had pancreatitis so they tested him and it came back positive for pancreatitis the doctor gave me a bunch of vitamins to start giving Franky but that didn’t seem to help his condition at all. he was still just wasting away.Franky would eat and eat and eat but he would just have horrible liquid diarrhea immediately after and he would have it constantly he could not control his diarrhea he was going in the bed on the floor everywhere. Also it is important to mention that Franky stopped laying down it was almost like he couldn’t lay down he would stand hunched almost in the shape of a muffin with his feet really close together he was stand right on the tips of his toes with his back hunched. I could tell that Franky was in so much pain at this point we did start giving him some subcutaneous pain medication and some subcutaneous fluids he seemed to feel a little better after this but still nothing was curing Franky. a vet technician suggested to me that Franky may have Cushing’s disease I was thinking this could be a possibility and I asked another vet if they would test Franky for this. The vet told me that I would be wasting my money because it is not very common for cats to get Cushing’s disease and she didn’t feel that his symptoms matched up. the day before Franky died I brought him back to the Animal Hospital to the same doctor who told me she didn’t think he had Cushing’s disease. I decided to have them do another ultrasound and this was about two months after the first ultrasound they had done. on this ultrasound they saw that he had an adrenal mass which they hadn’t been able to see on the last ultrasound 2 months ago. the veterinarian didn’t really tell me much as far as what she thought it meant. I told her I have read that an adrenal mass coincides with Cushing’s disease and she said that she could do the cushings test for me if I wanted to at that point but Frankys blood sugar had dropped at this point and he was in so much pain I did not want to put him through the test. I took him home that night and his temperature had dropped he was so cold and I warmed blankets in the dryer all night long to keep him warm. in the morning it was clear that Franky was not going to make it and I brought him into the vet and had him put to sleep. it was the hardest thing I’ve ever had to do in my life. I loved Franky and still love him so incredibly much I think about him constantly and I just wonder what it was that made him so sick .i wish i had noticed the symptoms a year before he got really sick he had not been sleeping in the bed with me he couldn’t he didn’t seem to get comfortable at night he was restless and he had a look of stress in his eyes but I didn’t pick up on the symptoms soon enough and once I realized it was too late. I tried everything I could think of to save him but nothing could. My question for you is, based off what I have written do you have any idea what could have caused his death? even if you aren’t correct that doesn’t matter I just can’t stop wondering what it was that made Franky so sick I just would like some suggestions based off the information I have given you as to what could have caused this.the question runs through my mind nearly every day and I just wonder what it was what would have caused the symptoms… was it cushings disease? Was it cancer? But if it was cancer then why were his symptoms starting over a year before with the restlessness and the distressing look in his eyes and how he stopped sleeping in the bed.I just need to know or at least have a better idea of what it could have been.. please give me anything you can think of… thank you very much for taking the time to read this and help me find some closure.

6 Responses

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  1. Bal Sal

    sorry about that man. but its very very rare that you will get anything usefull from this place. no good man

  2. Anonymous

    because you didn’t like the answers you were given does not mean helpful answers will not be given. your cat needed a vet. that was the end of the discussion. i’m sorry that you didn’t like this answer, but that’s the only answer any of us could give.

  3. Lindsay Ayers Post author

    I am not sure what you wrote even makes any sense. I never said I didnt like the vets answers… I just said the vets had no clue they didnt really gove me any answers they did bloodwork and an ultrasound and gave me meds to try but they never found out what why he was sick. I saw 5 vets no one had a clue and two of the vets were specialists. So what do u mean you’re sorry I didnt like the answer… What answers!!!!!! I feel like if you didnt have anything positive or helpful to say about my post you just shouldn’t have written. I am over here grieving my beloved cat and your just writing nonsense.

  4. Lindsay Ayers Post author

    Yea my cat needed a vet! I saw 5 and none of them had a clue. I used to be a vet technician for 7 years and now i am a registered nurse I have a clue about medicine and I took my cat to many vets. What is your post even saying!?!

  5. Lindsay Ayers Post author

    Thank you very much for responding. I do have 4 other cats and I love them all so much. I guess Franky was different because I feel like he loved me as well so much. My other cats love being with me too! But Franky was different when i would get home from work franky would be waiting for me when i opened the door and he would look at me and meow over and over lol he was so happy to see me. He would run down to my bed and jump on and just meow at me begging me to lay with him and when i did he would just purr and be so happy. My other cats show love too but not like that. He was so special , like a child to me. I guess youre right I have to accept never knowing and I am very happy I could rescue him when he was a kitten and give him about 10 wonderful years. He will always be in my heart everyday.

  6. Lindsay Ayers Post author

    I thought it would get easier but I cry ever time I think of him. It has been a year I hope in time it will get better. He just was so amazing. I really appreciate your sympathies.

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Ray Beck | 7 years ago
Is Clear Lung Chinese Herbal Formula Safe For Dogs On Prednisone And Amoxicillian, With Haveing…

is clear lung chinese herbal formula safe for dogs on prednisone and amoxicillian, with haveing possible heart disease or cushings disease or laringeal paralasys please help

3 Responses

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  1. Jana

    Lots of possibilities and no clear diagnosis. Not good. That’s shooting in the dark. And how would prednisone and antibiotics combo treat any of those things? Is there an additional lung condition such as inflammation, infection, flu …? I don’t see how would prednisone treatment mix with Cushing’s, which in itself is excess cortisol which then would be added further through the medication … ? I would not arbitrarily throw anything new into this mix.

    What I would seek is a definite diagnosis. Knowing what one is treating exactly is important for effectiveness and safety of the treatment.

    I appreciate you’re seeking non-drug solutions, I worked with TCVM in the past as well. However,  strongly recommend a consultation with an integrative vet who can put the pieces together, identify the issue(s) and formulate treatment that is tailored to your dog’s medical status.

  2. Ray Beck Post author

    i have seen my vet had xrays and ultra sounds blood work and we they still cannot determine what exactly is wrong with him first it was heart disease then they said it wasnt then they said it may be cushings or laringeal paralasys right now he cant breath well its way worse in humid conditions and his nose is crusty again im just looking for a reason to his breathing problem like reactions to amoxicillian or prednisone which could make breathing more difficult and possibly find something to help i feel im running out of time to save my buddy and to me it seems like someone should have an idea of what to do at this point

  3. Jana

    Yes, someone should have an idea at this point or should have referred you to a specialist. I think finding a new, integrative vet might be your best bet.
    a) they use the same tools conventional vets do (they can review all the existing labs etc, do their own if needed)
    b) they have their own different way of looking at things

    This might make them better suited to help identify the problem. I would seek one now.
    http://www.tcvm.com/

    We turned to TCVM when at our wit’s end and had some good results integrating it into our strategy. (This was with a superior vet and after consultation with specialists when nobody could figure out what was going on)

    Did they do Cushing’s-specific testing? Though some indications of it show up on routine blood work and on urinalysis (creatinine : cortisol ratio); which should help decide whether or not to proceed with ACTH Stim Test.
    http://www.veterinarypartner.com/Content.plx?A=636&

    Another option is an online consultation with an veterinary internist who specializes specifically in mysterious problems, Dr. Donna Spector
    http://www.spectordvm.com/

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Pat Staines | 9 years ago
We Are Fostering A Manchester Terroir And This Dog Is Always Hungry. We Feed…

We are fostering a Manchester terroir and this dog is always hungry. We feed him 3/4 cup of premium dog food twice a day. After he eats he is whining a couple of hours later for food. When it gets close to feeding time he whines barks and shakes until he is fed. He also drinks a lot of water. He is a rescue and he is about 8 years old. We have been told he was tested for cushings disease and it was negative. We are concerned about his health. He also has a lot of bowel movements. The bowel movements are solid. We do not want to over feed him. We are concerned there may be another health issue.

1 Response

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  1. Krista Magnifico

    Hello Ms Staines,

    Thank You for your question and most especially Thank You for fostering. Without people like you there would be no place for a pet to be loved and cared for between the time it takes for them to find their own home, outside of the shelter.

    Without knowing the weight of your dog and without an examination and the ability to review all of the previous diagnostics that have been done it is difficult to assess your dogs condition.

    But, I do always say that your dog knows better than any diagnostic, test, or procedure. If your dog is acting like they are starving, they are trying to tell you something.

    Perhaps a re-check with your veterinarian can help you further investigate your dogs insatiable appetite?

    I think that your concerns are all valid and should be discussed with your vet. Certainly over feeding has its own set of concerns and predisposes obesity, diabetes, heart and joint diseases, to name a few.

    I hope that this helps, and if you would like to discuss any of these items I would be happy to help.

    Thank you again for fostering, and best of luck with your pup.

    Sincerely,
    Krista

    Krista Magnifico, DVM
    Owner Jarrettsville Veterinary Center
    Jarrettsville, MD
    http://www.jarrettsvillevet.com

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TriciaR | 9 years ago
Hello,
My Father Has A 10yr Old Chihuahua That Is Very Obese. The Vet Has Run…

Hello,
My father has a 10yr old chihuahua that is very obese. The vet has run serveral test to include blood work, xrays, and stimulus test.
The vet suspected Cushing’s disease and the results were 2.7 prior to the test and 11.9 after. The results were negative for Cushing’s however the vet said that sometimes this test provides a false negative.
The blood work also showed levels of 2624 when he said the normal is 5-131. So basically he has a very enlarged liver and that is all we know.
The vet wants to bring in a specialist, Dr. Parkinson to perform an ultrasound and consult.
Question: Does this all sound correct and maybe on target? What would you do? and what do you think may be the prognosis?
My father loves little Bear so much but I hate to see him invest so much emotionally and financially if there is really no treatment.
Thank you so much for your time.
TriciR

1 Response

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  1. Krista Magnifico

    Hello,

    Thanks for your question and I’m sorry your dads dog is having such a difficult time.

    I think that you are talking about alkaline phosphatase when you say that one of the liver values was 2624, with the normal being between 5-131. This significant elevation is most commonly seen in cushings disease..

    There are two tests for Cushings. The ACTH stim test and the LDDT…if one is negative the other should be done to rule out the two possible causes..they are not cheap and it is frustrating if one comes back negative and you then have to do the other..I do think that an ultrasound is a very good place to go next..I also think that your dad should have a long frank discussion with his veterinarian before he continues to chase down this diagnosis. Here’s why, Cushings disease is also expensive to treat. Now mind you I would never try to dissuade someone from treating for an illness but I also do not want someone to spend money that they cannot afford to follow through with treating for.

    I have spoken with many internal medicine specialists (by the way another excellent resource for your dad to seek out, they aren’t cheap either but they can give him a very thorough treatment plan and recommendations), who say "there are two types of people who treat for Cushings, those who are being driven crazy by the non-stop drinking and urinating, and those that can afford and want to treat."

    In general I advise a specialist for anyone who wants very good and precise list of options for both diagnosing and treating a complex disease. I don’t ever think that this is a waste of money, but it is always really comforting to know what your options and associated costs are with each possible scenario.

    Another option is to ask for a second opinion at another general practitioners office, another set of eyes, and another way to explain this often helps with the decision making process.

    I hope that this helps,
    if you would like to talk to me, or anyone at our clinic, in Jarrettsville MD, we would be happy to chat.

    Oh, one last thing,,make sure you ask about a nutrition plan. And that all other relevant diagnostic tests, like urinalysis, bile acids, thyroid, and fecal have been done.

    Sincerely,
    Krista

    Krista Magnifico, DVM
    Owner Jarrettsville Veterinary Center
    Jarrettsville, MD
    http://www.jarrettsvillevet.com